Opodo lets you search flights to Palermo (PMO) all in one place. Compare timings, layovers and fares across every airline flying this route, then sort by journey length or departure time to settle on the best option for you.
Most flights land at Punta Raisi Airport (PMO), the main airport for Palermo.
Prefer a direct flight? Ryanair flies non-stop from Prague to Palermo.
Wizz Air Malta runs a further direct route from Prague, giving you another option to weigh up.
Ryanair is the airline travellers flying to Palermo pick most, making it a sensible starting point when you compare fares and schedules.
Recently, the best fare found on this route was €8, though the price you see will vary with your travel dates and times.
Add a hotel in Palermo to the same booking to unlock exclusive discounts.