Trains in Santa Cruz are 19% cheaper than in Panama City.
A meal in Santa Cruz is 57% cheaper than a meal in Panama City.
Taxis are 9% more expensive in Santa Cruz than in Panama City.
Coffee in Santa Cruz is 33% cheaper than in Panama City.
Discover cheap flights from Panama City to Santa Cruz with the Opodo search engine. By using our flight comparison tool, you'll be able to find your flight selection at the cheapest price available on the market. You can also filter price, timings, airports and more to find the best route to Santa Cruz that suits your needs. Using our 'smart choice' option, Opodo's engine will find the cheapest and most convenient flight out of the list of results, letting you save time and money on booking your flight from Panama City to Santa Cruz. Additionally, you can also book a hotel or a car for hire to complete your booking process. You can also download the Opodo App to save on flights and receive exclusive discounts by subscribing to our newsletter. Let us help you book the perfect holiday, save money and effort by using Opodo's flight search engine and enjoy your holiday knowing you got the best flight deals. So remember, introduce your flight details, hit search and you're on your way! The perfect holiday is just around the corner, book now.